Stromal response to Hedgehog signaling restrains pancreatic cancer progression

Pancreatic ductal adenocarcinoma (PDA) is the most lethal of common human malignancies, with no truly effective therapies for advanced disease. Preclinical studies have suggested a therapeutic benefit of targeting the Hedgehog (Hh) signaling pathway, which is activated throughout the course of PDA p...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Lee, John J., Perera, Rushika M., Wang, Huaijun, Wu, Dai-Chen, Liu, X. Shawn, Han, Shiwei, Fitamant, Julien, Jones, Phillip D., Ghanta, Krishna S., Kawano, Sally, Nagle, Julia M., Deshpande, Vikram, Boucher, Yves, Kato, Tomoyo, Chen, James K., Willmann, Jürgen K., Bardeesy, Nabeel, Beachy, Philip A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2014
विषय:
PNAS Plus
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121834/
https://ncbi.nlm.nih.gov/pubmed/25024225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411679111
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