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Predictive energy landscapes for folding α-helical transmembrane proteins
We explore the hypothesis that the folding landscapes of membrane proteins are funneled once the proteins’ topology within the membrane is established. We extend a protein folding model, the associative memory, water-mediated, structure, and energy model (AWSEM) by adding an implicit membrane potent...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4121805/ https://ncbi.nlm.nih.gov/pubmed/25030446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410529111 |
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