Decreased dopamine brain reactivity in marijuana abusers is associated with negative emotionality and addiction severity

Moves to legalize marijuana highlight the urgency to investigate effects of chronic marijuana in the human brain. Here, we challenged 48 participants (24 controls and 24 marijuana abusers) with methylphenidate (MP), a drug that elevates extracellular dopamine (DA) as a surrogate for probing the reac...

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Bibliografiske detaljer
Main Authors: Volkow, Nora D., Wang, Gene-Jack, Telang, Frank, Fowler, Joanna S., Alexoff, David, Logan, Jean, Jayne, Millard, Wong, Christopher, Tomasi, Dardo
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121778/
https://ncbi.nlm.nih.gov/pubmed/25024177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411228111
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