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The PmlI-PmlR Quorum-Sensing System in Burkholderia pseudomallei Plays a Key Role in Virulence and Modulates Production of the MprA Protease

Burkholderia pseudomallei is the causative agent of melioidosis, an often fatal infection of humans and animals. The virulence of this pathogen is thought to depend on a number of secreted proteins, including the MprA metalloprotease. We observed that MprA is produced upon entry into the stationary...

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Main Authors: Valade, E., Thibault, F. M., Gauthier, Y. P., Palencia, M., Popoff, M. Y., Vidal, D. R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC412159/
https://ncbi.nlm.nih.gov/pubmed/15060030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.8.2288-2294.2004
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