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The PmlI-PmlR Quorum-Sensing System in Burkholderia pseudomallei Plays a Key Role in Virulence and Modulates Production of the MprA Protease

Burkholderia pseudomallei is the causative agent of melioidosis, an often fatal infection of humans and animals. The virulence of this pathogen is thought to depend on a number of secreted proteins, including the MprA metalloprotease. We observed that MprA is produced upon entry into the stationary...

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Détails bibliographiques
Publié dans:J Bacteriol
Auteurs principaux: Valade, E., Thibault, F. M., Gauthier, Y. P., Palencia, M., Popoff, M. Y., Vidal, D. R.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2004
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Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC412159/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15060030/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.186.8.2288-2294.2004
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