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The PmlI-PmlR Quorum-Sensing System in Burkholderia pseudomallei Plays a Key Role in Virulence and Modulates Production of the MprA Protease

Burkholderia pseudomallei is the causative agent of melioidosis, an often fatal infection of humans and animals. The virulence of this pathogen is thought to depend on a number of secreted proteins, including the MprA metalloprotease. We observed that MprA is produced upon entry into the stationary...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Main Authors: Valade, E., Thibault, F. M., Gauthier, Y. P., Palencia, M., Popoff, M. Y., Vidal, D. R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC412159/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15060030/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.186.8.2288-2294.2004
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