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SMAD3 augments FoxO3-induced MuRF-1 promoter activity in a DNA-binding-dependent manner
Muscle-specific RING finger-1 (MuRF-1), a ubiquitin ligase and key regulator of proteasome-dependent protein degradation, is highly expressed during skeletal muscle atrophy. The transcription factor forkhead box O3 (FoxO3) induces MuRF-1 expression, but the direct role of other major atrophy-related...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4121583/ https://ncbi.nlm.nih.gov/pubmed/24920680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00391.2013 |
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