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Metabolic Reprogramming towards Aerobic Glycolysis Correlates with Greater Proliferative Ability and Resistance to Metabolic Inhibition in CD8 versus CD4 T Cells

T lymphocytes (T cells) undergo metabolic reprogramming after activation to provide energy and biosynthetic materials for growth, proliferation and differentiation. Distinct T cell subsets, however, adopt metabolic programs specific to support their needs. As CD4 T cells coordinate adaptive immune r...

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Autors principals: Cao, Yilin, Rathmell, Jeffrey C., Macintyre, Andrew N.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121309/
https://ncbi.nlm.nih.gov/pubmed/25090630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104104
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