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Costimulation endows immunotherapeutic CD8 T cells with IL-36-responsiveness during aerobic glycolysis
CD134 and CD137 primed CD8 T cells mount powerful effector responses upon recall, but even without recall these dual costimulated T cells respond to signal 3 cytokines like IL-12. We searched for alternative signal 3 receptor pathways and found the IL-1 family member IL-36R. While IL-36 alone did no...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4685023/ https://ncbi.nlm.nih.gov/pubmed/26573834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501217 |
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