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Prion (PrPC) Expression in Ovine Uteroplacental Tissues Increases after Estrogen-treatment in Ovariectomized (OVX) Ewes and during Early Pregnancy
Scrapie in sheep is spread laterally by placental transmission of an infectious misfolded form (PrPSc) of a normal prion protein (PrPC) used as a template in PrPSc formation. We hypothesized that PrPC would be expressed in uterine and placental tissues and estradiol-17B (E2) would affect uterine PrP...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4121124/ https://ncbi.nlm.nih.gov/pubmed/24664411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/REP-13-0548 |
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