Prion protein PrPc interacts with molecular chaperones of the Hsp60 family.
Prions mediate the pathogenesis of certain neurodegenerative diseases, including bovine spongiform encephalopathy in cattle and Creutzfeldt-Jakob disease in humans. The prion particle consists mainly, if not entirely, of PrPSc, a posttranslationally modified isoform of the cellular host-encoded prio...
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| Publicado no: | J Virol |
|---|---|
| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190409/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8676499/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.7.4724-4728.1996 |
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