Overexpression of active Syrian golden hamster prion protein PrPc as a glutathione S-transferase fusion in heterologous systems.

This article describes a procedure which permits for the first time the isolation of the prion protein PrPc from the Syrian golden hamster in heterologous systems. Using a glutathione S-transferase (GST) fusion approach, milligram amounts of stable, soluble, and homogeneous GST::PrPc protein were ob...

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Autors principals: Weiss, S, Famulok, M, Edenhofer, F, Wang, Y H, Jones, I M, Groschup, M, Winnacker, E L
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC189288/
https://ncbi.nlm.nih.gov/pubmed/7609044
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