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Overexpression of active Syrian golden hamster prion protein PrPc as a glutathione S-transferase fusion in heterologous systems.

This article describes a procedure which permits for the first time the isolation of the prion protein PrPc from the Syrian golden hamster in heterologous systems. Using a glutathione S-transferase (GST) fusion approach, milligram amounts of stable, soluble, and homogeneous GST::PrPc protein were ob...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Weiss, S, Famulok, M, Edenhofer, F, Wang, Y H, Jones, I M, Groschup, M, Winnacker, E L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189288/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7609044/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.8.4776-4783.1995
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