Antagonism of the Phosphatase PP1 by the measles virus V protein is required for innate immune escape of MDA5

The cytosolic sensor MDA5 is crucial for antiviral innate immune defense against various RNA viruses including measles virus; as such, many viruses have evolved strategies to antagonize the antiviral activity of MDA5. Here, we show that measles virus escapes MDA5 detection by targeting the phosphata...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Davis, Meredith E., Wang, May K., Rennick, Linda J., Full, Florian, Gableske, Sebastian, Mesman, Annelies W., Gringhuis, Sonja I., Geijtenbeek, Teunis B.H., Duprex, W. Paul, Gack, Michaela U.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120867/
https://ncbi.nlm.nih.gov/pubmed/25011105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.06.007
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados