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Inhibition of glutathione synthesis distinctly alters mitochondrial and cytosolic redox poise

The glutathione couple GSH/GSSG is the most abundant cellular redox buffer and is not at equilibrium among intracellular compartments. Perturbation of glutathione poise has been associated with tumorigenesis; however, due to analytical limitations, the underlying mechanisms behind this relationship...

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Autors principals: Kolossov, Vladimir L, Hanafin, William P, Beaudoin, Jessica N, Bica, Denisa E, DiLiberto, Stephen J, Kenis, Paul JA, Gaskins, H Rex
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120747/
https://ncbi.nlm.nih.gov/pubmed/24586100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214522179
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