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Inhibition of glutathione synthesis distinctly alters mitochondrial and cytosolic redox poise
The glutathione couple GSH/GSSG is the most abundant cellular redox buffer and is not at equilibrium among intracellular compartments. Perturbation of glutathione poise has been associated with tumorigenesis; however, due to analytical limitations, the underlying mechanisms behind this relationship...
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| Main Authors: | , , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4120747/ https://ncbi.nlm.nih.gov/pubmed/24586100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214522179 |
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