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Utilization of LC-MS/MS Analyses to Identify Site-Specific Chemical Protein Adducts In Vitro

Biologically reactive intermediates are formed following metabolism of xenobiotics, and during normal oxidative metabolism. These reactive species are electrophilic in nature and are capable of forming stable adducts with target proteins. These covalent protein modifications can initiate processes t...

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Detalhes bibliográficos
Main Authors: Fisher, Ashley A., Labenski, Matthew T., Monks, Terrence J., Lau, Serrine S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120700/
https://ncbi.nlm.nih.gov/pubmed/20972762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60761-849-2_19
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