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Utilization of LC-MS/MS Analyses to Identify Site-Specific Chemical Protein Adducts In Vitro

Biologically reactive intermediates are formed following metabolism of xenobiotics, and during normal oxidative metabolism. These reactive species are electrophilic in nature and are capable of forming stable adducts with target proteins. These covalent protein modifications can initiate processes t...

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Sonraí Bibleagrafaíochta
Main Authors: Fisher, Ashley A., Labenski, Matthew T., Monks, Terrence J., Lau, Serrine S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120700/
https://ncbi.nlm.nih.gov/pubmed/20972762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60761-849-2_19
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