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Utilization of LC-MS/MS Analyses to Identify Site-Specific Chemical Protein Adducts In Vitro

Biologically reactive intermediates are formed following metabolism of xenobiotics, and during normal oxidative metabolism. These reactive species are electrophilic in nature and are capable of forming stable adducts with target proteins. These covalent protein modifications can initiate processes t...

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Hlavní autoři: Fisher, Ashley A., Labenski, Matthew T., Monks, Terrence J., Lau, Serrine S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120700/
https://ncbi.nlm.nih.gov/pubmed/20972762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60761-849-2_19
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