The Frequency of 1,4-Benzoquinone-Lysine Adducts in Cytochrome c Correlate with Defects in Apoptosome Activation

Electrophile-mediated post-translational modifications (PTMs) are known to cause tissue toxicities and disease progression. These effects are mediated via site-specific modifications and structural disruptions associated with such modifications. 1,4-Benzoquinone (BQ) and its quinone-thioether metabo...

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Detalhes bibliográficos
Main Authors: Fisher, Ashley A., Labenski, Matthew T., Malladi, Srinivas, Chapman, John D., Bratton, Shawn B., Monks, Terrence J., Lau, Serrine S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Molecular Toxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203403/
https://ncbi.nlm.nih.gov/pubmed/21527774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr085
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