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Utilization of LC-MS/MS Analyses to Identify Site-Specific Chemical Protein Adducts In Vitro
Biologically reactive intermediates are formed following metabolism of xenobiotics, and during normal oxidative metabolism. These reactive species are electrophilic in nature and are capable of forming stable adducts with target proteins. These covalent protein modifications can initiate processes t...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4120700/ https://ncbi.nlm.nih.gov/pubmed/20972762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60761-849-2_19 |
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