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Prediction of HIV drug resistance from genotype with encoded three-dimensional protein structure

BACKGROUND: Drug resistance has become a severe challenge for treatment of HIV infections. Mutations accumulate in the HIV genome and make certain drugs ineffective. Prediction of resistance from genotype data is a valuable guide in choice of drugs for effective therapy. RESULTS: In order to improve...

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Main Authors: Yu, Xiaxia, Weber, Irene T, Harrison, Robert W
格式: Artigo
語言:Inglês
出版: BioMed Central 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120140/
https://ncbi.nlm.nih.gov/pubmed/25081370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-S5-S1
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