Pharmacometabolomics Reveals That Serotonin Is Implicated in Aspirin Response Variability

While aspirin is generally effective for prevention of cardiovascular disease, considerable variation in drug response exists, resulting in some individuals displaying high on-treatment platelet reactivity. We used pharmacometabolomics to define pathways implicated in variation of response to treatm...

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Detalhes bibliográficos
Main Authors: Ellero-Simatos, S, Lewis, J P, Georgiades, A, Yerges-Armstrong, L M, Beitelshees, A L, Horenstein, R B, Dane, A, Harms, A C, Ramaker, R, Vreeken, R J, Perry, C G, Zhu, H, Sànchez, C L, Kuhn, C, Ortel, T L, Shuldiner, A R, Hankemeier, T, Kaddurah-Daouk, R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120016/
https://ncbi.nlm.nih.gov/pubmed/25029353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/psp.2014.22
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