Pharmacometabolomics Reveals That Serotonin Is Implicated in Aspirin Response Variability

While aspirin is generally effective for prevention of cardiovascular disease, considerable variation in drug response exists, resulting in some individuals displaying high on-treatment platelet reactivity. We used pharmacometabolomics to define pathways implicated in variation of response to treatm...

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書誌詳細
主要な著者: Ellero-Simatos, S, Lewis, J P, Georgiades, A, Yerges-Armstrong, L M, Beitelshees, A L, Horenstein, R B, Dane, A, Harms, A C, Ramaker, R, Vreeken, R J, Perry, C G, Zhu, H, Sànchez, C L, Kuhn, C, Ortel, T L, Shuldiner, A R, Hankemeier, T, Kaddurah-Daouk, R
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2014
主題:
Original Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120016/
https://ncbi.nlm.nih.gov/pubmed/25029353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/psp.2014.22
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