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Integration of Pharmacometabolomic and Pharmacogenomic Approaches Reveals Novel Insights Into Antiplatelet Therapy

Interindividual variability in response to antiplatelet therapy results in higher platelet reactivity as well as higher rates of cardiovascular events. Despite substantial effort, the genetic and nongenetic determinants of antiplatelet variability remain poorly understood. Emerging pharmacometabolom...

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Detalhes bibliográficos
Main Authors: Lewis, JP, Yerges-Armstrong, LM, Ellero-Simatos, S, Georgiades, A, Kaddurah-Daouk, R, Hankemeier, T
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116100/
https://ncbi.nlm.nih.gov/pubmed/23892404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2013.153
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