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Characterisation of Familial Colorectal Cancer Type X, Lynch syndrome, and non-familial colorectal cancer

BACKGROUND: Familial Colorectal Cancer Type X (FCCTX) is defined as individuals with colorectal cancer (CRC) who families meet Amsterdam Criteria-1 (AC1), but whose tumours are DNA-mismatch-repair-proficient, unlike Lynch syndrome (LS). FCCTX does not have an increased risk of extra-colonic cancers....

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Autors principals: Shiovitz, S, Copeland, W K, Passarelli, M N, Burnett-Hartman, A N, Grady, W M, Potter, J D, Gallinger, S, Buchanan, D D, Rosty, C, Win, A K, Jenkins, M, Thibodeau, S N, Haile, R, Baron, J A, Marchand, L L, Newcomb, P A, Lindor, N M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119982/
https://ncbi.nlm.nih.gov/pubmed/24918813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.309
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