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Inference and validation of predictive gene networks from biomedical literature and gene expression data

Although many methods have been developed for inference of biological networks, the validation of the resulting models has largely remained an unsolved problem. Here we present a framework for quantitative assessment of inferred gene interaction networks using knock-down data from cell line experime...

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Main Authors: Olsen, Catharina, Fleming, Kathleen, Prendergast, Niall, Rubio, Renee, Emmert-Streib, Frank, Bontempi, Gianluca, Haibe-Kains, Benjamin, Quackenbush, John
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119824/
https://ncbi.nlm.nih.gov/pubmed/24691108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2014.03.004
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