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Inference and validation of predictive gene networks from biomedical literature and gene expression data

Although many methods have been developed for inference of biological networks, the validation of the resulting models has largely remained an unsolved problem. Here we present a framework for quantitative assessment of inferred gene interaction networks using knock-down data from cell line experime...

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Detalhes bibliográficos
Main Authors: Olsen, Catharina, Fleming, Kathleen, Prendergast, Niall, Rubio, Renee, Emmert-Streib, Frank, Bontempi, Gianluca, Haibe-Kains, Benjamin, Quackenbush, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119824/
https://ncbi.nlm.nih.gov/pubmed/24691108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2014.03.004
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