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Structural Basis for a pH Sensitive Calcium Leak across Membranes

Calcium homeostasis balances passive calcium leak and active calcium uptake. Human Bax inhibitor 1 (hBI-1) is an anti-apoptotic protein that mediates a calcium leak and is representative of highly conserved and widely distributed family, the transmembrane Bax inhibitor motif (TMBIM) proteins. Here w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chang, Yanqi, Bruni, Renato, Kloss, Brian, Assur, Zahra, Kloppmann, Edda, Rost, Burkhard, Hendrickson, Wayne A., Liu, Qun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119810/
https://ncbi.nlm.nih.gov/pubmed/24904158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1252043
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