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Origins of the specificity of tissue-type plasminogen activator.

The role of subsite interactions in defining the stringent substrate specificity of tissue-type plasminogen activator (t-PA) has been examined by using an fd phage library that displayed random hexapeptide sequences and contained 2 x 10(8) independent recombinants. Forty-four individual hexapeptides...

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Detalhes bibliográficos
Main Authors: Ding, L, Coombs, G S, Strandberg, L, Navre, M, Corey, D R, Madison, E L
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC41198/
https://ncbi.nlm.nih.gov/pubmed/7644467
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