Origins of the specificity of tissue-type plasminogen activator.
The role of subsite interactions in defining the stringent substrate specificity of tissue-type plasminogen activator (t-PA) has been examined by using an fd phage library that displayed random hexapeptide sequences and contained 2 x 10(8) independent recombinants. Forty-four individual hexapeptides...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
1995
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41198/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7644467/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.17.7627 |
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