A reporter mouse reveals lineage-specific and heterogeneous expression of IRF8 during lymphoid and myeloid cell differentiation()

The interferon regulatory factor family member 8 (IRF8) regulates differentiation of lymphoid and myeloid lineage cells by promoting or suppressing lineage-specific genes. How IRF8 promotes hematopoietic progenitors to commit to one lineage while preventing the development of alternative lineages is...

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Main Authors: Wang, Hongsheng, Yan, Ming, Sun, Jiafang, Jain, Shweta, Yoshimi, Ryusuke, Abolfath, Sanaz Momben, Ozato, Keiko, Coleman, William G., Ng, Ashley P., Metcalf, Donald, DiRago, Ladina, Nutt, Stephen L., Morse, Herbert C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119573/
https://ncbi.nlm.nih.gov/pubmed/25024380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301939
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