The differential regulation of human ACT1 isoforms by Hsp90 in IL-17 signaling()

IL-17 is a pro-inflammatory cytokine implicated in the pathogenesis of autoimmune diseases including psoriasis. ACT1 is an essential adaptor molecule in the IL-17 signaling pathway. A missense single nucleotide polymorphism (rs33980500; SNP-D10N) that resulted in the substitution of an asparagine fo...

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Hlavní autoři: Wu, Ling, Wang, Chenhui, Boisson, Bertrand, Misra, Saurav, Rayman, Patricia, Finke, James H., Puel, Anne, Casanova, Jean-Laurent, Li, Xiaoxia
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119565/
https://ncbi.nlm.nih.gov/pubmed/25024377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400715
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