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Bcl-2 regulation of the inositol 1,4,5-trisphosphate receptor and calcium signaling in normal and malignant lymphocytes: Potential new target for cancer treatment

The anti-apoptotic protein Bcl-2 is a versatile regulator of cell survival. Its interactions with its own pro-apoptotic family members are widely recognized for their role in promoting the survival of cancer cells. These interactions are thus being targeted for cancer treatment. Less widely recogniz...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Greenberg, Edward F., Lavik, Andrew R., Distelhorst, Clark W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119508/
https://ncbi.nlm.nih.gov/pubmed/24642270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2014.03.008
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