A G-Protein Subunit Translocation Embedded Network Motif Underlies GPCR Regulation of Calcium Oscillations

G-protein βγ subunits translocate reversibly from the plasma membrane to internal membranes on receptor activation. Translocation rates differ depending on the γ subunit type. There is limited understanding of the role of the differential rates of G(βγ) translocation in modulating signaling dynamics...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Giri, Lopamudra, Patel, Anilkumar K., Karunarathne, W.K. Ajith, Kalyanaraman, Vani, Venkatesh, K.V., Gautam, N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2014
Gaiak:
Systems Biophysics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119271/
https://ncbi.nlm.nih.gov/pubmed/24988358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.05.020
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