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G-protein signaling leverages subunit-dependent membrane affinity to differentially control βγ translocation to intracellular membranes
Activation of G-protein heterotrimers by receptors at the plasma membrane stimulates βγ-complex dissociation from the α-subunit and translocation to internal membranes. This intermembrane movement of lipid-modified proteins is a fundamental but poorly understood feature of cell signaling. The differ...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529095/ https://ncbi.nlm.nih.gov/pubmed/23213235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205345109 |
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