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Regulation of Golgi structure and secretion by receptor-induced G protein βγ complex translocation

We show that receptor induced G protein βγ subunit translocation from the plasma membrane to the Golgi allows a receptor to initiate fragmentation and regulate secretion. A lung epithelial cell line, A549, was shown to contain an endogenous translocating G protein γ subunit and exhibit receptor-indu...

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Detalhes bibliográficos
Main Authors: Saini, Deepak Kumar, Karunarathne, W. K. Ajith, Angaswamy, Nataraju, Saini, Deepti, Cho, Joon-Ho, Kalyanaraman, Vani, Gautam, Narasimhan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895111/
https://ncbi.nlm.nih.gov/pubmed/20534534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003042107
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