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Optically triggering spatiotemporally confined GPCR activity in a cell and programming neurite initiation and extension
G-protein–coupled receptor (GPCR) activity gradients evoke important cell behavior but there is a dearth of methods to induce such asymmetric signaling in a cell. Here we achieved reversible, rapidly switchable patterns of spatiotemporally restricted GPCR activity in a single cell. We recruited prop...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3637763/ https://ncbi.nlm.nih.gov/pubmed/23479634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220697110 |
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