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ERK1/2/COX-2/PGE(2) signaling pathway mediates GPR91-dependent VEGF release in streptozotocin-induced diabetes
PURPOSE: Retinal vascular dysfunction caused by vascular endothelial growth factor (VEGF) is the major pathological change that occurs in diabetic retinopathy (DR). It has recently been demonstrated that G protein-coupled receptor 91 (GPR91) plays a major role in both vasculature development and ret...
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| Main Authors: | , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Molecular Vision
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4119234/ https://ncbi.nlm.nih.gov/pubmed/25324681 |
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