IgG galactosylation aberrancy precedes disease onset, correlates with disease activity and is prevalent in autoantibodies in rheumatoid arthritis

OBJECTIVE: To examine the association of IgG galactosylation aberrancy with disease parameters in rheumatoid arthritis (RA). METHODS: N-glycan analysis of serum from multiple cohorts was performed. IgG N-glycan content and timing of N-glycan aberrancy relative to disease onset was compared in health...

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Главные авторы: Ercan, Altan, Cui, Jing, Chatterton, Dereck E.W., Deane, Kevin D., Hazen, Melissa M., Brintnell, William, O’Donnell, Colin I., Derber, Lezlie A., Weinblatt, Michael E., Shadick, Nancy A., Bell, David A., Cairns, Ewa, Solomon, Daniel H., Holers, V. Michael, Rudd, Pauline M., Lee, David M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118465/
https://ncbi.nlm.nih.gov/pubmed/20506563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27533
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