Forces and Dynamics of Glucose and Inhibitor Binding to Sodium Glucose Co-transporter SGLT1 Studied by Single Molecule Force Spectroscopy

Single molecule force spectroscopy was employed to investigate the dynamics of the sodium glucose co-transporter (SGLT1) upon substrate and inhibitor binding on the single molecule level. CHO cells stably expressing rbSGLT1 were probed by using atomic force microscopy tips carrying either thioglucos...

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Xehetasun bibliografikoak
Egile Nagusiak: Neundlinger, Isabel, Puntheeranurak, Theeraporn, Wildling, Linda, Rankl, Christian, Wang, Lai-Xi, Gruber, Hermann J., Kinne, Rolf K. H., Hinterdorfer, Peter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2014
Gaiak:
Molecular Biophysics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118126/
https://ncbi.nlm.nih.gov/pubmed/24962566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.529875
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