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Modulation of Triglyceride and Cholesterol Ester Synthesis Impairs Assembly of Infectious Hepatitis C Virus

In hepatitis C virus infection, replication of the viral genome and virion assembly are linked to cellular metabolic processes. In particular, lipid droplets, which store principally triacylglycerides (TAGs) and cholesterol esters (CEs), have been implicated in production of infectious virus. Here,...

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Hlavní autoři: Liefhebber, Jolanda M. P., Hague, Charlotte V., Zhang, Qifeng, Wakelam, Michael J. O., McLauchlan, John
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118089/
https://ncbi.nlm.nih.gov/pubmed/24917668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.582999
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