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Modulation of Triglyceride and Cholesterol Ester Synthesis Impairs Assembly of Infectious Hepatitis C Virus

In hepatitis C virus infection, replication of the viral genome and virion assembly are linked to cellular metabolic processes. In particular, lipid droplets, which store principally triacylglycerides (TAGs) and cholesterol esters (CEs), have been implicated in production of infectious virus. Here,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liefhebber, Jolanda M. P., Hague, Charlotte V., Zhang, Qifeng, Wakelam, Michael J. O., McLauchlan, John
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118089/
https://ncbi.nlm.nih.gov/pubmed/24917668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.582999
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