Tensin-4-Dependent MET Stabilization Is Essential for Survival and Proliferation in Carcinoma Cells

Inappropriate MET tyrosine kinase receptor signaling is detected in almost all types of human cancer and contributes to malignant growth and MET dependency via proliferative and antiapoptotic activities. Independently, Tensin-4 (TNS4) is emerging as a putative oncogene in many cancer types, but the...

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Autors principals: Muharram, Ghaffar, Sahgal, Pranshu, Korpela, Taina, De Franceschi, Nicola, Kaukonen, Riina, Clark, Katherine, Tulasne, David, Carpén, Olli, Ivaska, Johanna
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118019/
https://ncbi.nlm.nih.gov/pubmed/24814316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.03.024
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