Tensin-4-Dependent MET Stabilization Is Essential for Survival and Proliferation in Carcinoma Cells

Inappropriate MET tyrosine kinase receptor signaling is detected in almost all types of human cancer and contributes to malignant growth and MET dependency via proliferative and antiapoptotic activities. Independently, Tensin-4 (TNS4) is emerging as a putative oncogene in many cancer types, but the...

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Detalhes bibliográficos
Main Authors: Muharram, Ghaffar, Sahgal, Pranshu, Korpela, Taina, De Franceschi, Nicola, Kaukonen, Riina, Clark, Katherine, Tulasne, David, Carpén, Olli, Ivaska, Johanna
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118019/
https://ncbi.nlm.nih.gov/pubmed/24814316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.03.024
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