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Evaluating bias-reducing protocols for RNA sequencing library preparation
BACKGROUND: Next-generation sequencing does not yield fully unbiased estimates for read abundance, which may impact on the conclusions that can be drawn from sequencing data. The ligation step in RNA sequencing library generation is a known source of bias, motivating developments in enzyme technolog...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4117970/ https://ncbi.nlm.nih.gov/pubmed/25001197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-569 |
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