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Systematic comparison of small RNA library preparation protocols for next-generation sequencing
BACKGROUND: Next-generation sequencing technologies have revolutionized the study of small RNAs (sRNAs) on a genome-wide scale. However, classical sRNA library preparation methods introduce serious bias, mainly during adapter ligation steps. Several types of sRNA including plant microRNAs (miRNA), p...
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Publicado no: | BMC Genomics |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5799908/ https://ncbi.nlm.nih.gov/pubmed/29402217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-4491-6 |
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