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Free mRNA in excess upon polysome dissociation is a scaffold for protein multimerization to form stress granules
The sequence of events leading to stress granule assembly in stressed cells remains elusive. We show here, using isotope labeling and ion microprobe, that proportionally more RNA than proteins are present in stress granules than in surrounding cytoplasm. We further demonstrate that the delivery of s...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4117795/ https://ncbi.nlm.nih.gov/pubmed/25013173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku582 |
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