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Inventory of telomerase components in human cells reveals multiple subpopulations of hTR and hTERT

Telomerase is the ribonucleoprotein (RNP) enzyme that elongates telomeric DNA to compensate for the attrition occurring during each cycle of DNA replication. Knowing the levels of telomerase in continuously dividing cells is important for understanding how much telomerase is required for cell immort...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xi, Linghe, Cech, Thomas R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117779/
https://ncbi.nlm.nih.gov/pubmed/24990373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku560
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