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TET-mediated oxidation of methylcytosine causes TDG or NEIL glycosylase dependent gene reactivation
The discovery of hydroxymethyl-, formyl- and carboxylcytosine, generated through oxidation of methylcytosine by TET dioxygenases, raised the question how these modifications contribute to epigenetic regulation. As they are subjected to complex regulation in vivo, we dissected links to gene expressio...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4117777/ https://ncbi.nlm.nih.gov/pubmed/24948610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku552 |
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