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The elusive evidence for chromothripsis

The chromothripsis hypothesis suggests an extraordinary one-step catastrophic genomic event allowing a chromosome to ‘shatter into many pieces’ and reassemble into a functioning chromosome. Recent efforts have aimed to detect chromothripsis by looking for a genomic signature, characterized by a larg...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kinsella, Marcus, Patel, Anand, Bafna, Vineet
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117757/
https://ncbi.nlm.nih.gov/pubmed/24939897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku525
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